The competition began with the group stage in September 2024, and will conclude with the Nations League Finals in March 2025.

CONCACAF Nations League continued to be played in the format introduced for 2023–24 season.

The four best-ranked teams according to the CONCACAF Ranking Index received a bye to the quarter-finals.

[3] The remaining twelve teams entered the group stage using a Swiss-system tournament format.

Unlike previous editions, matches were not played in standard home-and-away format.

If a team was unable to host matches, CONCACAF reserved the right to select a venue.