Fixtures for the 2024–25 season were announced on 10–12 September 2024, following the draw for each region.
[1][2][3] The season started on 9 October 2024, and will conclude in May 2025.
The first-placed team in each group in the promotion play-off round earns promotion to the Egyptian Second Division A next season.
Teams finishing bottom in each group during the regular season face relegation to the Egyptian Third Division.
Originally, only 13 teams were promoted from the Third Division, but due to administrative errors, the Egyptian Football Association made a decision on 16 August 2024 to promote two additional teams, Benha and Al Jazeera, following appeals from both clubs.