For the draw, the teams were seeded into 10 pots, in accordance with the Club Ranking, based on their performance in European competitions during a three-year period and the lowest possible position that any club from that league can occupy in the draw is calculated by adding the results of the worst performing team from each league.
There were scheduling restrictions: for example, teams from the same city in general were not scheduled to play at home on the same round (to avoid them playing at home on the same day or on consecutive days, due to logistics and crowd control).
This restriction was applied to the two teams from Israel (Hapoel Bank Yahav Jerusalem and Hapoel Shlomo Tel Aviv) that play their home games at Arena Samokov in Samokov, Bulgaria due to the Israel–Hamas war.
Moreover, the top two teams in each regular season group will receive first round playoff byes, skipping the octafinals to be placed directly into the quarterfinals.
At the tail end of the standings, four teams from each group will be eliminated after the regular season.