The winners earned a place in the second qualifying round of the 2025–26 UEFA Conference League.
Seven preliminary round matches were played on 7 December 2024, featuring the teams from the 2024–25 Maltese Challenge League, 2024–25 Gozo First Division, and the four semi-finalists of the 2024–25 Maltese National Amateur League.
However, thirteen teams were awarded a bye to the first round The draw was held on 12 November 2024 by Malta FA Director of Football Operations Stephen Azzopardi.
[1] Sixteen matches played between 10–12 January, featuring the seven preliminary round winners, the 14 teams from the 2024–25 Maltese Premier League, and the eight teams given preliminary round byes.
The draws were held by Malta FA Director of Football Operations Stephen Azzopardi together with former Malta national team player Andrew Cohen and Byron Falzon Commercial Officer of IZIBET.