On June 23, 2024, Muangthong United announced that the club had parted ways with Miloš Joksić after the contract expired at the end of 2023-24 season.

[1][2] Muangthong United appointed Gino Lettieri as the new head coach on July 6, 2024.

[4] On July 23, 2024, Vietnamese club Dong A Thanh Hoa announced that they would withdraw from the 2024–25 AFC Champions League Two campaign due to a hectic schedule in the upcoming 2024-25 season.

Therefore, the AFC sent an official letter to the FA Thailand stating that a Thai club would replace Dong A Thanh Hoa spot.

Hence, Muangthong United who finished 5th in the 2023-24 Thai League 1 season, gets the chance to compete in the group stage round of 2024–25 AFC Champions League Two instead.