The 2024–25 SMU Mustangs women's basketball team will represent Southern Methodist University during the 2024–25 NCAA Division I women's basketball season.

The Mustangs will be led by fourth-year head coach Toyelle Wilson and will play their home games at Moody Coliseum in University Park, Texas.

[a] They will compete as first year members of the Atlantic Coast Conference.

As the eleventh seed in the AAC tournament, they lost to the fourteenth seed Tulane in the First Round.

They were not invited to the NCAA tournament or the WBIT.