The Orange, led by second-year head coach Adrian Autry, play their home games at JMA Wireless Dome in Syracuse, New York as twelfth-year members of the Atlantic Coast Conference.

Syracuse lost the tiebreaker and was the seventh seed in the ACC tournament.

They faced tenth-seed NC State for the third time this season in the Second Round and NC State avenged both regular season losses by defeating the Orange 83–65.

[1] Sources: On October 15, 2024, the ACC released the preseason coaches poll.

Syracuse was picked to finish 11th in the ACC regular season, its lowest ranking in the poll since joining the conference in 2013.