The competition is conducting during the ongoing war with the Russia since late February 2022.

In total the first stage will have 18 rounds with 72 matches in each group, 16 for each team.

[1] The teams' record from the previous stage will be grandfathered in full.

[1] The teams' record from the previous stage will be grandfathered in full as well.

[1] Following the withdrawal of FC Khust in September 2024, the Professional Football League adopted following decisions:[2] This season, Ukrainian First League consisted of 18 teams.

Two teams were relegated at the end of the 2023–24 Ukrainian Premier League.

Due to the Russian military aggression, three clubs in the league were forced to relocate.