Defending champion Aryna Sabalenka defeated Zheng Qinwen in the final, 6–3, 6–2 to win the women's singles tennis title at the 2024 Australian Open.

By reaching the final, Zheng made her debut in the top ten of the WTA rankings.

[10] For the first time in the tournament's history, there were six former champions in the main draw: Sabalenka, Naomi Osaka, Sofia Kenin, Caroline Wozniacki, Angelique Kerber, and Azarenka.

[11] This was the final Australian Open appearance for 2016 champion Kerber, who lost to Danielle Collins in the first round.

The entry list was released by Tennis Australia based on the WTA rankings for the week of 4 December 2023.