The women's 4 × 400 metres relay at the 2024 European Athletics Championships took place in two rounds at the Stadio Olimpico in Rome, Italy, on 11 and 12 June 2024.

[5] The world leading time was 3:21.70 min, set by the team of the United States on 5 May 2024, and the European leading time was 3:24.38 min, set by the team of Ireland on 4 May 2024, both during the 2024 World Athletics Relays in Nassau, Bahamas.

[8] (Tatyana Ledovskaya, Olga Nazarova, Mariya Pinigina, Olga Bryzgina) (Kirsten Emmelmann, Sabine Busch, Petra Müller, Marita Koch) (Quanera Hayes, Gabrielle Thomas, Bailey Lear, Alexis Holmes) (Sophie Becker, Rhasidat Adeleke, Phil Healy, Sharlene Mawsdley) Sixteen national teams could qualify for the women's 4 × 400 metres relay.

[9][10] The other fifteen teams qualified by their ranking based on the aggregate of their two fastest times during the qualification period from 1 January 2023 to 26 May 2024.

[1] Lieke Klaver was the first leg runner for the Netherlands and the first to hand over the baton after one round, followed by Sophie Becker of Ireland, Kinga Gacka of Poland, and Naomi Van den Broeck of Belgium.

[11] In the anchor leg, Femke Bol was in the lead from handover to finish, and Sharlene Mawdsley of Ireland and Helena Ponette of Belgium were not able to pass her and maintained their relative positions.