Danielle Collins defeated Elena Rybakina in the final, 7–5, 6–3 to win the women's singles tennis title at the 2024 Miami Open.

53, Collins became the lowest-ranked women's singles champion, the second lowest-ranked finalist in the tournament's history (after Naomi Osaka in 2022), and the oldest first-time WTA 1000 champion since Elena Vesnina at the 2017 Indian Wells Open.

Collins lost only one set en route to the title, in the first round against Bernarda Pera.

[5][6] Rybakina became the first woman to reach consecutive Miami Open finals since Serena Williams from 2013 to 2015.

[7] This tournament marked the final appearance of former Canadian Open champion Camila Giorgi, who later officially announced her retirement on 7 May 2024.