Andrey Rublev defeated Félix Auger-Aliassime in the final, 4–6, 7–5, 7–5 to win the men's singles tennis title at the 2024 Madrid Open.

Auger-Aliassime was the first Canadian singles finalist since the tournament's inception in 2002 and the first to reach a Masters 1000 final on clay.

[3] Daniil Medvedev became the fifth player born in the 1990s (after Dominic Thiem, Stefanos Tsitsipas, Alexander Zverev, and Grigor Dimitrov) to reach at least the quarterfinals at all nine ATP Masters 1000 events,[4] and the tenth active player overall to accomplish the feat.

[5] Taylor Fritz became the first American man to reach the semifinals of the tournament since Robby Ginepri in 2005, and the first since it switched to clay courts in 2009.

He is defending points from an ATP Challenger Tour event held during the second week of the 2023 tournament instead.