Although the season was originally expected to begin on 14 February 2025,[1] delays in the resolution of disciplinary cases that could affect the club composition for the season eventually forced the start date to be moved to early April.
16 teams will compete in the league for the 2025 season: the top 14 teams in the aggregate table of the 2024 Primera División season, along with ABB who promoted from the 2024 Copa Simón Bolívar, and the winners of the promotion/relegation play-off Totora Real Oruro.
ABB achieved a first-ever promotion to the top tier on 1 December 2024, after winning the Copa Simón Bolívar title.
[3] Meanwhile, Totora Real Oruro's first-ever promotion was confirmed on 6 January 2025, after the Bolivian Football Federation's Sports Disciplinary Court ruled the exclusion of Royal Pari from the competition following their abandonment of the second leg of the promotion/relegation play-off.
[4] ABB and Totora Real Oruro replaced Real Santa Cruz and Royal Pari, both relegated to the Santa Cruz regional league.