The 2025 Purdue Boilermakers football team is an American football team that will represent Purdue University in the Big Ten Conference during the 2025 NCAA Division I FBS football season.

The Boilermakers will play home games at Ross–Ade Stadium in West Lafayette, Indiana.

The team is expected to be led head coach Barry Odom, in his first season in the post.

at Ross–Ade Stadium • West Lafayette, Indiana at Ross–Ade Stadium • West Lafayette, Indiana at Ross–Ade Stadium • West Lafayette, Indiana at Notre Dame Stadium • Notre Dame, Indiana at Ross–Ade Stadium • West Lafayette, Indiana at Huntington Bank Stadium • Minneapolis, Minnesota at Martin Stadium • Evanston, Illinois at Ross–Ade Stadium • West Lafayette, Indiana at Michigan Stadium • Ann Arbor, Michigan at Ross–Ade Stadium • West Lafayette, Indiana at Husky Stadium • Seattle, Washington at Ross–Ade Stadium • West Lafayette, Indiana