The 2045 Initiative is a nonprofit organization that develops a network and community of researchers in the field of life extension, focusing on combining brain emulation and robotics to create forms of cyborgs.

[6] The main goal of the 2045 Initiative, as stated on its website, is "to create technologies enabling the transfer of an individual’s personality to a more advanced non-biological carrier, and extending life, including to the point of immortality.

We devote particular attention to enabling the fullest possible dialogue between the world’s major spiritual traditions, science and society".

On the biological side, a life support system will be developed for hosting a human brain inside the avatar and maintaining it alive and functional.

Martine A. Rothblatt, the founder of United Therapeutics, has claimed the Avatar Project is "no more wild than in the early '60s, when we saw the advent of liver and kidney transplants.