The Brigade's mission was to performs a wide variety of functions ranging from the delivery of rocket artillery fires to operating a field hospital.

The 214th Field Artillery Brigade maintained a high state of combat readiness for priority worldwide contingency missions and supported Fort Sill with medical, personnel, transportation, aviation, engineer, maintenance, and chemical assets.

The 214th Fires Brigade was first constituted on 3 February 1944 in the Army of the United States as the Headquarters and Headquarters Battery, 214th Field Artillery Group and was assigned to XXI Corps, 4th US Army, at Fort Polk, Louisiana.

After activation at Camp Van Dorn, Mississippi, the Group moved to Fort Sill, Oklahoma on 18 November 1944 for training.

It remained inactive until 15 October 1958, when it was reactivated and assigned to the United States Army Artillery and Missile Center at Fort Sill, Oklahoma.

3-13th Field Artillery was subsequently transferred to the 75th Fires Brigade, also at Fort Sill, Oklahoma.