It operates Buk M1 missile systems and is subordinated to the Air Command West.

In January 1992, following the Dissolution of the Soviet union, the personnel of the 223rd Anti-Aircraft Missile Brigade of the 38th Combined Arms Army took an oath of loyalty to Ukraine.

[1] The 223rd Anti-aircraft Missile Regiment was stationed in Terebovlia, Ternopil Oblast till 2004 when it was relocated to Stryi, Lviv Oblast at the base of the disbanded 25th Anti-aircraft Missile Brigade.

[3] In November 2018, the 223rd regiment's Buk M1 systems took part in a firing competition in Kherson Oblast with two systems securing the 1st and 2nd places in the competition for which they were awarded 150k and 90k hyrvnias respectively and the regiment was considered the best [4] On 23 August 2021, the regiment was awarded the honorary title "Ukrainian Sich Riflemen" after the Legion of Ukrainian Sich Riflemen, a unit of the Austro-Hungarian Army that saw combat during the World War I and later the Polish–Ukrainian War as a part of Ukrainian People's Army.

[5] During the Russian invasion of Ukraine, the regiment was deployed for combat operations.