The brigade was originally formed in 1953 as an engineering brigade operating Scud missiles, serving in western Ukraine until its 1958 relocation to the Group of Soviet Forces in Germany in East Germany.

It included the 229th, 232nd, and 234th Separate Engineering Battalions, and a technical battery, and in October 1953 it was transferred to Bilokorovychi, in northern Ukraine, armed with R-11 Scud missiles.

In 1962, it consisted of the 106th and 160th Separate Missile Battalions and a technical battery, with the 106th at Meissen and the 160th at Bischofswerda.

Between 23 June and 17 July 1981, the brigade was relocated to Birobidzhan,[2] where it became part of the 43rd Army Corps.

[6] In 2005, it was announced that the brigade would begin rearming in 2007 with the updated 9K720 Iskander-M tactical ballistic missile system.