25 St Ann Street in Manchester, England, is a Victorian bank with attached manager's house constructed in 1848 for Heywood's Bank by John Edgar Gregan.

[1] The bank is "one of the finest palazzo-inspired buildings in the city.

"[1] It is a Grade II* listed building as of 25 February 1952.

[2] The bank is built of sandstone, "beautifully finished",[1] while the manager's house is of more modest red brick.

The bank and the manager's house are linked by a single-storey entrance, "an arrangement recalling the Palazzo Pandolfini in Florence.