The .22 Nosler is designed to use the existing bolt face of an AR-15, and conversions to this caliber can be accomplished with a simple barrel swap.

The case diameter and taper resemble those of the 6.8mm Remington SPC, so Nosler recommends using a magazine designed for that cartridge.

[4][3][5] The name .26 Nosler refers to the first two digits in the caliber (0.264 in; 6.7 mm) of the bullets that the cartridge fires and the name of the company which created it.

The .26 Nosler is designed as a modern 6.5mm cartridge, using recent advances in firearm technology to attain exceptionally high muzzle velocities, up to 1,040 m/s (3,400 ft/s), and maintain an extremely flat trajectory.

The overall cartridge length of 84.8 mm (3.340 in) is the same as that of the .30-06 Springfield, allowing the use of widely available standard-length actions.

[8] When released, the .26 Nosler was claimed to be the most powerful commercial 6.5 mm cartridge in the world.

[9] The .26 Nosler, when loaded with 8.4 g (129 gr) AccuBond Long Range very-low-drag bullets, retains as much velocity at 370 m (400 yd) as the .260 Remington produces at the muzzle.

The cases’ overall length also aids in quick follow-up shots, since the bolt throw is shorter than on a magnum action.

[16] The .28 Nosler is essentially a shortened version of the 7mm Remington Ultra Magnum (7mm RUM).

The dimension at that point on the .28 Nosler case is 0.051 mm (0.002 in) larger, and that reduces its body taper by just a tad.

Due to its greater length, the Remington case is about 25 percent more capacious than the Nosler.

[17] Since the .28 Nosler burns smaller powder charges than the 7mm RUM, barrel accuracy life is potentially a bit longer.

Introduced in 2016 (production release 2017), the .33 Nosler is a SAAMI approved and standardized cartridge.

The name .33 Nosler refers to the first two digits in the caliber (0.338 in; 8.6 mm) of the bullets that the cartridge fires and the name of the company which created it.

[16] The .33 Nosler is built on the same action length as the .338 Winchester Magnum but launches projectiles at a higher velocity.