The 28th Ohio Infantry Regiment was organized at Camp Dennison near Cincinnati, Ohio, beginning June 10, 1861, and mustered in July 6, 1861, for three years service under the command of Colonel August Moor.
The regiment was attached to 2nd Brigade, Army of Occupation, West Virginia, to October 1861.
2nd Brigade, Kanawha Division, IX Corps, Army of the Potomac, to October 1862.
2nd Brigade, Kanawha Division, District of West Virginia, Department of the Ohio, to March 1863.
Averill's 4th Separate Brigade, VIII Corps, Middle Department, to June 1863.
The 28th Ohio Infantry mustered out of service at Wheeling, West Virginia, on July 13, 1865.
March to Camp Lookout and Big Sewell Mountain September 15–23.
Moved to New Creek June 17, thence to Beverly July 2–7, and duty there until November 1.
Averill's Raid from Beverly against Lewisburg and the Virginia & Tennessee Railroad November 1–17.
March to Webster on the Baltimore & Ohio Railroad with 1,000 prisoners, wounded and refugees, June 8–18.