The squadron was an integral part of the United States' Post Attack Command and Control System, performing the Operation Looking Glass mission with the Boeing EC-135 aircraft.

[1] The 2d Liaison Squadron provided emergency air evacuation, search and rescue, courier and messenger service, routine reconnaissance and transportation of personnel.

It regularly operated between Langley Air Force Base, Virginia and Fort John Custis with one Beechcraft C-45 Expeditor and several Stinson L-13s.

[1] In July 1952, the squadron closed at Langley and reopened at Shaw Air Force Base, South Carolina, operating de Havilland Canada L-20 Beavers.

Eventually, on 1 April 1970, the 2nd ACCS took over the Looking Glass mission flying EC-135C ABNCP aircraft for the duration of the Cold War as a critical member in the Post Attack Command and Control System.