The architects, Haldeman Miller Bregman Hamann (now BOKA Powell), built the outside with brownish-reddish granite and black windows, and capped the skyscraper with a copper-colored dome.

The architects intended 300 North Meridian's design to echo the adjacent Chamber of Commerce building.

300 North Meridian is primarily used for office space, although 9 of its floors are occupied by a parking garage.

As of February 2014, 17.5% of the usable office space is vacant,[5] and the building is owned by REI Real Estate Services.

[6][7] One of the main tenants of 300 North Meridian is the law firm Faegre Drinker Biddle & Reath, known as Baker & Daniels at the time of construction.