Part of the group moved overseas to RAF Bury St Edmunds, England, November–December 1942; planes and crews followed, March–April 1943.

In common with other Marauder units of the 3d Bomb Wing, the 322d was transferred to Ninth Air Force on 16 October 1943.

On 11 December 1943 Andrews Field was attacked by the Luftwaffe but little damage was done and beginning in March 1944 the 322d bombed railway and highway bridges, oil tanks, and missile sites in preparation for the invasion of Normandy.

Another B-26, "Flak Bait" (41-31773) survived to the end of hostilities with 202 missions to its credit, the only US bomber involved in combat over Europe to pass the 200 mark.

Afterwards, during the Normandy campaign, the 322d pounded fuel and ammunition dumps, bridges, and road junctions, supporting the Allied offensive at Caen and the breakthrough at Saint-Lô in July.

After V-E Day, the group was assigned to occupation duty in Germany beginning in June 1945, engaging in inventorying and disassembling German Air Force equipment and facilities.

During the Cold War, the 322d was redesignated the 322d Bombardment Group, Light and activated in the Air Force reserve at Reading Army Airfield, Pennsylvania on 9 August 1947.

The 322d was inactivated on 1 January 1959 along with the closure of Foster Air Force Base in a budgetary economy move.