[1] Originally written in 2007, its world première was held at Arena Stage in Washington, D.C.[2][3] before continuing on to La Jolla Playhouse in 2008.
The progression of her Amyotrophic lateral sclerosis (ALS) and her relationship with her daughter are also themes of the story, as is Beethoven's growing deafness.
[5] 33 Variations premièred at Arena Stage in September 2007, with Mary Beth Peil as Katherine, Laura Odeh as her daughter Clara, and Graeme Malcolm as Beethoven.
A West Coast production ran in April 2008 at La Jolla Playhouse's Mandell Weiss Theatre, with Jayne Atkinson as Katherine, Zach Grenier as Beethoven, and Odeh returning as Clara.
[5] Sets by Derek McLane; costumes by Janice Pytel; lighting by David Lander; sound by André J. Pluess; projection design by Jeff Sugg; choreography by Daniel Pelzig.