The 33rd Infantry Brigade Combat Team deployed to Afghanistan in December 2008 in support of Operation Enduring Freedom and re-deployed in September 2009.

The post-World War II reorganization of the Army National Guard included the 33rd and 44th Infantry Divisions as Illinois-based units.

[2] The 33rd Infantry Division continued until 1968, when it was inactivated as part of a National Guard force reduction.

[8] Soldiers of the 66th Brigade were activated for homeland security duty following the September 11th, 2001 terrorist attacks.

The brigade is routinely seen in archival footage, performing crowd control duties during the protests that accompanied the 1968 Democratic National Convention.