The group initially formed as a fun passion-project between Mincolla and Swafford,[1] who lived down the street from each other in Los Angeles.

[4][5] The band took the name 3Teeth from the concepts of Odontomancy, which Mincolla described as an ancient form of divination where "the seer would read prophecies in the teeth like rune stones.

[10] Nick Rossi joined the live band in Fall 2019 as a temporary replacement for Hanson, who had injured his foot on the European tour earlier that year.

Their self-titled debut album was released in 2014[11] and reached the number eight spot on iTunes Electronic Music Chart.

[14][15] The album was mixed by Sean Beavan, who is best known for working with other prominent industrial artists Nine Inch Nails and Marilyn Manson.

[24] The title for the third album, Metawar, was announced on April 5, 2019, alongside the release of the debut single "American Landfill".

[29][30] The video was directed by Matthew Santoro, longtime-friend of Alexis Mincolla and Hollywood director and visual effects artist whose credits include X-Men Origins: Wolverine and 300.

[29] The second single for Metawar, "EXXXIT", was released on April 23, 2019, alongside a music video[31][32] and a North American tour announcement with Author & Punisher and GOST as support.

[35] The single was accompanied by a music video featuring Mincolla as a neo-fascist lizard-man president in "band's most outwardly political song to date.

[41][42][43] While touring in support of Metawar in 2019, the band recorded one original track and two cover songs for the film Guns Akimbo.

[63][64][65] The group opened for German band Rammstein for some of their U.S. dates in the summer of 2017[66] and ended the year performing with Danzig and HIM.

[67] 3Teeth were selected by Rammstein to open for them on their special New Year's Eve performances in Mexico in December 2018 / January 2019.

[74] The COVID-19 pandemic forced the band to cancel the remainder of their 2020 shows two days before the Meta-X Tour with Carnifex was slated to commence, however.

[77][87] The band has been compared to bands/artists such as Ministry, Skinny Puppy, Nine Inch Nails, Marilyn Manson, KMFDM, Bile, Dope, Rob Zombie, Rammstein, and Tool.

[2][80][84][86][87][15] Lead vocalist, Alexis Mincolla, listens to bands like Sepultura, Pantera, White Zombie, and Nine Inch Nails.