In October, the 3rd Ohio Infantry was shipped to Louisville, Kentucky, and served for the rest of the war in the Western Theater.

After wintering near Elizabethtown, Kentucky, the regiment, then in the army of Ormsby Mitchel, was part of the general advance on Confederate-held Nashville, Tennessee, in February 1862.

The 3rd Ohio remained in Alabama until late August when it was part of the Union forces that pursued Braxton Bragg's Confederate army during the Kentucky Campaign.

Two weeks later, it marched back to Murfreesboro and remained there through the winter, participating in the Battle of Stones River at year's end.

[1] In June, the regiment helped quell the Holmes County Rebellion, and a month later was involved in the pursuit of Morgan's Raiders.