[1] Lieutenant Governor Judith Guichon agreed and Clark appointed a cabinet of 21 ministers and 13 parliamentary secretaries, which were sworn in on June 12, 2017.

[12] The cabinet was largely the same as the 40th Parliament, but with Sam Sullivan and Linda Reid, as well as newcomers Jordan Sturdy, Ellis Ross, and Jas Johal replacing ministers who had retired or were defeated in the election.

This cabinet only served during the Parliament's first session in which it lost a confidence vote and Clark resigned as an MLA, triggering a by-election in the Kelowna West riding.

[13] The first session of the 41st Parliament began on June 22, 2017, with the Speech from the Throne delivered by Lieutenant Governor Guichon on behalf of the Premier Clark and the BC Liberal government.

Acknowledging the split results of the election, the speech included not only BC Liberal election promises but also some from the opposition parties, such as banning corporate and union political donations, a maximum donation limit for individuals, a referendum on electoral reform, repealing the referendum requirement for new TransLink revenue sources, eliminating tolls on the Port Mann Bridge, and raising the carbon tax to $50 a tonne.

The ban on corporate, union and foreign donations was implemented with the Election Amendment Act, 2017 (Bill 3) and Local Elections Campaign Financing Amendment Act, 2017 (Bill 15) which required all political contributions be made by a resident of British Columbia and sets new maximum donation limits, including limits to third party sponsors, and political spending limits, as well as public subsidies until the year 2022 for the political parties who achieved 5% of the vote in their electoral districts (e.g. the BC NDP, BC Liberal and BC Green parties).

Ben Stewart joined the legislative assembly as a result of the February 14 by-election in Kelowna West to replace former-Premier Christy Clark.

[28] Other legislation related to health included the creation of the Voluntary Blood Donations Act (Bill 29) to prohibit payment for blood donations, subject to certain exemptions; related to the opioid epidemic, the Pill Press and Related Equipment Control Act (Bill 27) to limit who can lawfully own a pill press and to allow for a registry of equipment to be maintained by the government; the Opioid Damages and Health Care Costs Recovery Act (Bill 38) to allow the provincial government to launch an aggregate action lawsuit against opioid manufacturers and wholesalers who misled the public concerning the addictive and harmful nature of opioids;[29] and the Workers Compensation Act was amended to add a new mental disorder presumption for first responders and, at the request of the federal government, extended cancer presumptions to federally employed firefighters.

Without division, Bill 47 repealed the 37th Parliament's Health and Social Services Delivery Improvement Act and the Health Sector Partnerships Agreement Act which enabled contract-flipping in the healthcare sector,[30] Bill 50 re-established the Human Rights Commission for British Columbia which had been abolished by the same Parliament, and Bill 41 repealed the 37th Parliament's Public Education Flexibility and Choice Act which had removed the BC Teachers' Federation ability to negotiate class size and composition, and had led to teacher strikes, but was mostly struck down by the Supreme Court of Canada.

[32] The Public Interest Disclosure Act (Bill 28) was adopted to protect whistleblowers as recommended in the Ombudsperson's Misfire report concerning the inappropriate employment terminations within the Ministry of Health – Bill 13 was also implemented a recommendation of the same report, in this case to allow for the Merit Commissioner to review the process used in any dismissal within the public service.

[33] Bill 11 modernized the province's International Commercial Arbitration Act by bringing it in line with guidelines of the UN Commission on International Trade Law and Bill 21 brought the province's legislation concerning opting in or out of class action lawsuits into line with the Uniform Law Conference of Canada's guidelines.

[41] Legislative amendments related to money laundering included Bill 23, which created the Land Owner Transparency Act to require a land-owning corporation, trust or partnership to report beneficial ownership.

[44][45] Addressing threats from organized crime, the Witness Security Act (Bill 4) was adopted to establish a confidential, voluntary witness security program to supplement the federal version[46] and Bill 13 amended the Community Safety Act to allow a dedicated enforcement unit to accept and investigate confidential complaints about properties that are a threat to the safety of the community.

[47] New legislation, adopted with all-party support, included the Declaration on the Rights of Indigenous Peoples Act (Bill 41) to implement the UNDRIP,[48] the Protection of Public Participation Act (Bill 2) to address strategic lawsuits against public participation;[49] the Ticket Sales Act (Bill 27) to ban the use of automated ticket-purchasing software, mandate secondary ticket sellers disclose the additional fees added to the original price, and provide refunds for cancelled events or unusable (e.g. counterfeit) tickets;[50] the Zero-Emission Vehicles Act (Bill 28), to create a framework with targets for increasing the proportion of new zero-emission light-duty motor vehicles that are sold or leased in BC;[51] and the Fuel Price Transparency Act (Bill 42), to require businesses involved in the transporting, marketing and supplying of gasoline and diesel to provide data to the BC Utilities Commission on how fuel prices are set.

[55] Addressing employment and labour standards, Bill 8 raised the minimum work age from 12 to 14, prohibited employers from withholding or deducting tips from wages, and created a new allowance of unpaid leave for victims of domestic violence or critical illness,[56] while Bill 30 removed teachers from the list of essential services and further addressed contract-flipping by extending protections to re-tendered service (janitorial, security, transportation, health) contracts.

It reconvened for one day, March 23, with 10 MLAs in attendance, when they adopted a $5-billion aid package and amendments to the Employment Standards Act to create an unpaid "COVID-19-related leave".

Additional COVID-19-related legislation included Bills 18 and 19 which postponed penalties for non-payment of several taxes, created a $1,000 supplement to the Canada Emergency Response Benefit, and allowed provincial budget deficits for the next 3 years.