The squadron was first organized during World War II in the Mediterranean Theater of Operations as a ferrying unit.

MATS operations at Grenier were short-lived, however and in November 1955 the squadron moved to McGuire Air Force Base, New Jersey,[1] where it was inactivated.

Reactivated in 1961 at Travis Air Force Base, California[2] as a Boeing C-135 Stratolifter strategic airlift squadron, it operated these aircraft over the Pacific and around the world transport routes under MATS.

It was inactivated in 1972 due to budget restrictions as part of the post-Vietnam drawdown of the USAF.

[citation needed] This article incorporates public domain material from the Air Force Historical Research Agency