[2] Under the command of Lieutenant Colonel Valery Chvey, the brigade conducted its first Tochka launches at Kapustin Yar in November 1989 and received a satisfactory rating.

The 465th participated in a tactical exercise in August 1991 and was expanded by the formation of the 587th Separate Missile Battalion, since disbanded, on 1 December of that year.

[4] According to International Institute for Strategic Studies Military Balance 2022 estimates, Belarus had 36 launchers remaining in its inventory, all operated by the 465th.

[8] Between 2016 and 2021, the brigade conducted four Tochka-U launches, as well as the one during the Soyuznaya reshimost (Allied Resolve) joint exercise with Russia days before the 2022 Russian invasion of Ukraine began partially from Belarusian territory.

[10][11] The Belarusian Ministry of Defense announced on 1 February 2023 that a battalion of Iskander systems had entered full autonomous operation with the 465th Brigade.