On September 19, 1864, a detachment of the regiment along with soldiers from the 3rd Missouri State Militia Cavalry Regiment (Union) under the command of First Lieutenant Erich Pape, captured the town of Doniphan, Missouri, and burned most of it, including the court house, to the ground.
[1] The Union horse soldiers then retreated, burning farm houses and barns as they went.
Confederate cavalry under Gen. Joseph Shelby caught up with them the next morning at Ponder's Mill, in Butler County and killed four, wounded four and captured six.
[2][3][4] Elements of the regiment participated in the Battle of Pilot Knob and in delaying maneuvers before St. Louis during Price's Missouri Raid.
The regiment also performed guard duty at Spring Hill, Columbia, and Pulaski, Tennessee through March 1865.