This uniform consisted of a Federal dark blue 4 button sack coat, dark blue chasseur trousers, tan gaiters, and a maroon zouave fez with a light blue tassel.

The regiment's first lieutenant colonel was a future prominent politician and civil engineer, William Ward Duffield.

Several other soldiers in the regiment reached post-war prominence, including politician George Spalding and Major General Alfred E. Bates, who enlisted as privates in Company A.

The regiment's veterans and recruits were assigned to the 1st Michigan Infantry.The Fourth Michigan Infantry was reorganized under orders of July 26, 1864 and mustered into Federal service as a regiment on October 14, 1864.

[2] The regiment suffered 12 officers and 177 enlisted men who were killed in action or mortally wounded and 1 officer and 107 enlisted men who died of disease, for a total of 297 fatalities.