The 4th Missouri Infantry Regiment was formed on April 28, 1862, and served in the Confederate States Army during the American Civil War.

As part of Brigadier General Martin E. Green's brigade, the regiment participated in three charges against Union lines on October 3, 1862, during the Second Battle of Corinth.

After undergoing a prisoner exchange, the men rejoined the Confederate Army and served in the Atlanta Campaign and the Battle of Franklin in 1864, still as part of the 1st and 4th Missouri Infantry Regiment (Consolidated).

When the American Civil War began in 1861, the state of Missouri was politically divided between those supporting secession and those wishing to remain in the Union.

[1] The MSG, under the command of Major General Sterling Price, had initial success, including a victory against the Union Army in the Battle of Wilson's Creek,[2] but were confined to southwestern Missouri by the end of the year.

[3] In the Battle of Pea Ridge, fought on March 7 and 8, 1862, in northwestern Arkansas, Price and the MSG suffered another defeat while serving under Major General Earl Van Dorn.

Major General Ulysses S. Grant, who was the Union commander in the region, attempted to trap Price before he could join Van Dorn, but the Confederates were able to escape after fighting the Battle of Iuka.

[12] At this time, the 4th Missouri Infantry was in Brigadier General Martin E. Green's brigade, which was held in reserve and did not fight at Iuka.

On October 2, Union Major General William S. Rosecrans occupied Corinth with 23,000 men; that same day, he learned of Van Dorn's approach.

[14] The 4th Missouri Infantry and the rest of Green's brigade (except for the artillery) attacked an outer Union position held by Brigadier General Thomas A. Davies's division.

Command of Green's brigade then fell to Colonel William H. Moore,[17] who led a charge against the inner Union line, to capture a fortification known as Battery Powell.