The street runs eastbound from 12th Avenue, across the full width of the island, ending at Beekman Place.

The Park West Educational Campus is on 50th Street between Eleventh and Tenth Avenues.

[2] The Paramount Plaza building at Broadway was used in Silent Movie as the location of the "Engulf and Devour" company.

At the northeast corner with Madison Avenue are the Villard Houses and Lotte New York Palace Hotel.

One block east, at the northeast corner with Park Avenue, is the Waldorf Astoria New York.