52872 Okyrhoe /oʊˈkɪroʊ.iː/ is a centaur orbiting in the outer Solar System between Jupiter and Saturn.

It was discovered on 19 September 1998, by the Spacewatch survey at Kitt Peak Observatory in Arizona, United States, and named after Ocyrhoe from Greek mythology.

Centaurs have short dynamical lives due to strong interactions with the giant planets.

[9] Of objects listed as a centaur by the Minor Planet Center (MPC),[4] JPL,[2] and the Deep Ecliptic Survey (DES),[3] Okyrhoe has the second smallest perihelion distance of a numbered centaur.

Okyrhoe passed perihelion in early 2008,[2] and exhibited significant magnitude variations during March and April 2008.