The 52nd Annual GMA Dove Awards presentation ceremony was held on Tuesday, October 19, 2021 at the Allen Arena located in Nashville, Tennessee.

The ceremony recognized the accomplishments of musicians and other figures within the Christian music industry for the year 2021.

[1] CeCe Winans won the most awards, with 4 including Gospel Artist of the Year, alongside producer Jason Ingram and worship band Elevation Worship, who both also clinched 4 awards each, the latter winning Song of the Year for "The Blessing".

[2] The nominations were announced on August 11, 2021, during a livestream event which was broadcast on the GMA Dove Awards' Facebook page and YouTube channel.

[3] The event featured Alex Campos, John Cooper, Bill and Gloria Gaither, Kari Jobe, Brian and Jenn Johnson, Jonathan McReynolds, Wande and Tauren Wells as the announcers.