Designed by local architect John Young, the building is Category B listed, dating to 1881.

[1] Standing on Tay Street, the building was originally the museum home of the Perthshire Society of Natural Science, constructed in memory of Sir Thomas Moncreiffe, 7th Baronet, a past president of the society.

[1] The museum housed two exhibits: a local (or regional) collection (which contained a collection of the animals, plants and rocks to be found in Perthshire and the basin of the Tay) and The Type (or Index) Museum, which illustrated the main types of animals, plants and rocks.

[1] The northern end of the building (numbers 68–72) were destroyed by a fire in 1987.

[1] Number 63 is the home of restaurant 63 Tay Street,[3] owned by Graeme Pallister.