[1] The 621st consists of approximately 1500 airmen in six groups, fourteen squadrons and more than 20 geographically separated operating locations aligned with major Army and Marine Corps combat units.

[1] The 621st CRW is highly specialized in training and rapidly deploying personnel to quickly open airfields and establish, expand, sustain, and coordinate air mobility operations.

From wartime taskings to disaster relief, the 621st extends Air Mobility Command's (AMC) reach in deploying people and equipment around the globe.

[2] Most of the operations can be classified by three types: Joint Task Force - Port Opening (JTF-PO), where USAF and US Army units create distribution chains; Expeditionary Air Mobility Support, (EAMS) where CRW personnel augment existing forces for the mission; and Initial Airbase Opening (IAO).

[3] The 621st included four groups, eight squadrons and ten geographically separated operating locations aligned with major US Army and Marine Corps combat units.

[8] Once deployed, they provided additional aerial port capabilities to increase aircraft loading efficiency for the Pakistan Air Force's Central Flood Relief Cell.