It was last assigned to the USAF Weapons School at Whiteman Air Force Base, Missouri, where it served from 2003 until 9 September 2005 as an advanced training unit with the Northrop Grumman B-2 Spirit.

After training in the United States, it deployed to the European Theater of Operations, and served in the strategic bombing campaign against Germany with the 448th Bombardment Group.

The ground echelon moved to Camp Shanks, New York and sailed for England aboard the RMS Queen Elizabeth on 23 November.

It bombed V-weapon launch sites, airfields and transportation facilities to support Operation Overlord, the invasion of Normandy, and on D-Day attacked coastal defenses and choke points on German lines of communication.

The B-50 gave the unit the capability to carry heavy loads of conventional weapons faster and farther as well as being designed for atomic bomb missions if necessary.

By 1951, the emergence of the Soviet Mikoyan-Gurevich MiG-15 interceptor in the skies of North Korea signaled the end of the propeller-driven B-50 as a first-line strategic bomber.

The squadron moved into the jet age when it received new, swept wing Boeing B-47 Stratojets in 1955 which were designed to carry nuclear weapons and to penetrate Soviet air defenses with its high operational ceiling and near supersonic speed.

The squadron began to send its Stratojets to the Aerospace Maintenance and Regeneration Center at Davis-Monthan Air Force Base, Arizona for retirement in 1965, and the unit inactivated in 1966.