It was mustered in for three years service on March 27, 1862, under the command of Colonel Granville Moody.
The regiment was attached to Dumont's Independent Brigade, Army of the Ohio, to June 1862.
7th Brigade, 8th Division, Army of the Ohio, to November 1862.
3rd Brigade, 2nd Division, Center, XIV Corps, Army of the Cumberland, to January 1863.
3rd Brigade, 2nd Division, XIV Corps, Army of the Cumberland, to October 1863.
3rd Brigade, 1st Division, XIV Corps, to June 1865.
2nd Brigade, 1st Division, XIV Corps, to July 1865.
The 74th Ohio Infantry mustered out of service at Louisville, Kentucky, on July 11, 1865.
Ordered to Camp Chase, Ohio, February 24, 1862, and duty there until April 20.
Guard duty along railroad between Nashville and Columbia, Tenn., until September 3.
Passage of the Cumberland Mountains and Tennessee River and Chickamauga Campaign August 16-September 22.
Davis Cross Roads or Dug Gap September 11.
Operations on line of Pumpkin Vine Creek and battles about Dallas, New Hope Church and Allatoona Hills May 25-June 5.