80 Sappho (symbol: )is a large, S-type (stony) main-belt asteroid.

It was discovered by English astronomer Norman Pogson on 2 May 1864, and is named after Sappho, the Archaic Greece poet.

The asteroid is orbiting the Sun at a distance of 2.2957 AU with a period of 3.48 years and an eccentricity (ovalness) of 0.2.

[4] 13-cm radar observations of this asteroid from the Arecibo Observatory between 1980 and 1985 were used to produce a diameter estimate of 83 kilometres (52 mi).

[8] Hanuš et al. (2013) confirmed the polar axis has ecliptic coordinates (λ, β) = (194°, −26°) and listed a rotation period of 14.03087 h.[6] Sappho (at apparent magnitude 11.8) occulted the magnitude 7.2 star HIP 24403 in the constellation of Taurus on 16 September 2018 at 8:54 UT.