Engaged in antisubmarine operations over the Gulf of Mexico and the Caribbean Sea as part of the III Bomber Command, May– July 1942.

While the 93rd was at RAF Alconbury, His Majesty, King George VI paid his first visit to an Eighth Air Force base on 13 November 1942.

The group receiving a Distinguished Unit Citation for operations in that theatre, December 1942 – February 1943, when, with inadequate supplies and under the most difficult desert conditions, the detachment struck heavy blows at enemy shipping and communications.

The detachment returned to England in February 1943, where its personnel were featured on the cover of the 26 July 1943 issue of Life Magazine and the unit dubbed "Ted's Traveling Circus" after its first commander, Col. Edward J. Timberlake.

From February 1943 and until the end of June the group bombed engine repair works, harbors, power plants, and other targets in France, the Low Countries, and Germany.

A detachment returned to the Mediterranean theatre during June and July 1943 to support the Allied invasion of Sicily and to participate in the famous low-level attack on enemy oil installations at Ploesti on 1 August.

Having followed another element of the formation along the wrong course to Ploesti, the 93rd hit targets that had been assigned to other groups, but it carried out its bombing of the vital oil installations despite heavy losses inflicted by attacks from the fully alerted enemy and was awarded a Distinguished Unit Citation for the operation.

The detachment rejoined the group in October 1943, and until April 1945 the 93rd concentrated on bombardment of strategic targets such as marshalling yards, aircraft factories, oil refineries, chemical plants, and cities in Germany.

The 93rd Bombardment Group ceased combat operations in April 1945, and returned to Sioux Falls Army Air Field South Dakota during May/June for B-29 Superfortress transition training, prior to deployment to the Pacific Theater.

However, the operations of the reestablished group was short, On 1 June 1992 the 93rd was relieved from assignment to SAC and was reassigned to the newly formed Air Combat Command (ACC).

Deployed to Southwest Asia in response to Iraq's refusal to cooperate with United Nations weapons inspectors, 18 February – 3 June 1998.

Between 23 February – 28 June 1999, deployed aircraft and personnel to Ramstein Air Base, Germany to assist in monitoring Serbian withdrawal from Kosovo.