In 1851, with his father, he published Catalogue méthodique de la collection des Reptiles.

[1] With zoologist Marie Firmin Bocourt (1819–1904), he collaborated on a project called Mission scientifique au Mexique et dans l'Amérique Centrale, a publication that was the result of Bocourt's scientific expedition to Mexico and Central America from 1864 to 1866.

The section on reptiles is considered to be Dumeril's best written effort in the field of herpetology.

[2][3] Duméril died in 1870 during the siege of Paris, and Mission scientifique au Mexique et dans l'Amérique Centrale was continued by Bocourt, Léon Vaillant (1834–1914) and other scientists.

As part of the Collection des Suites à Buffon, he issued a two-volume ichthyological study titled Histoire naturelle des poissons, ou Ichtyologie générale (1865, 1870),[4][5] research that complemented the works of Georges Cuvier (1769–1832) and Achille Valenciennes (1794–1865) by describing species not covered by the two famous naturalists.