The A725 road in Scotland is a major route which is a trunk road dual carriageway for almost its whole length,[2] connecting several of the large towns of North Lanarkshire and South Lanarkshire, linking the M8 and M74 motorways; it has been upgraded frequently since its construction, with the most recent major work completed in 2017.

In combination with the A726 road which meets the M77 motorway, it forms a southern and eastern bypass for the city of Glasgow.

[3] The northern section of the A725 begins to the east of Glasgow in Coatbridge town centre where it meets the A89; it runs south through the Whifflet and Shawhead neighbourhoods, then links with the A8 and M8 (Junction 7A) in a complex, partially grade-separated junction at Shawhead[4] and travels south past Bellshill, flanked by two large industrial estates that have a dedicated exit, with additional exits at Belziehill for central Bellshill and Viewpark (A721), and for Orbiston.

The A725 continues as the East Kilbride Expressway, a dual carriageway running south-west around Bothwell, crossing over the River Clyde then immediately dipping under the historic Bothwell Bridge, through High Blantyre (with exits for the A724 (Low Blantyre / Burnbank), Hamilton, and the University of the West of Scotland campus) on to Nerston in the north of East Kilbride.

There, it links with the A749 (which runs to Rutherglen and south-eastern Glasgow) at the Whirlies Roundabout – a short spur was constructed between the two roads in the 1990s to bypass the Whirlies and ease congestion (at the same time, traffic lights were added to the major roads joining the roundabout).