The film contains 26 shorts, each by different directors spanning fifteen countries, including Nacho Vigalondo, Kaare Andrews, Adam Wingard, Simon Barrett, Banjong Pisanthanakun, Ben Wheatley, Lee Hardcastle, Noboru Iguchi, Ti West, and Angela Bettis.

The winner was UK-based director Lee Hardcastle, who submitted the claymation short for T.[7] The film begins showing a close up of a funnel with blood pouring ominously from it.

The consensus reads: "As often the case with anthology films, The ABCs of Death is wildly uneven, with several legitimately scary entries and a bunch more that miss the mark".

[9] The Austin Chronicle says it "soars to such artistic heights, and such tasteless depths, on a global scale, no less, bodes well for the future of cinema fantastique and otherwise",[10] while Inside Pulse says the movie has a "brilliant concept but not great execution".

Any viewer should be prepared to laugh pretty hard; feel tense; get grossed out like they would at any halfway decent horror film.

[17] After showing the film to a group of high school Spanish students, former Ohio substitute teacher Sheila Kearns was found guilty of four counts of disseminating matter harmful to juveniles.