ACS Macro Letters is a peer-reviewed scientific journal published by the American Chemical Society.

As of 2017[update], ACS Macro Letters has the highest impact factor of any journal in the field of polymer science (6.131).

[2] Examining both synthetic and naturally occurring polymers, ACS Macro Letters reports major advances in polymer synthesis, modification reactions, characteristics, theory, simulation, surface properties, and kinetics and mechanisms.

The journal reports on all areas of soft matter science where macromolecules play a key role, including nanotechnology, self-assembly, supramolecular chemistry, biomaterials, energy, and sustainable materials.

[6] ACS Macro Letters enables researchers in the field to bring their important findings in polymer science and related disciplines to the attention of the global scientific community.