2JOD11711517ENSG00000078549ENSMUSG00000029778P41586P70205NM_001118NM_001199635NM_001199636NM_001199637NM_001025372NM_007407NP_001109NP_001186564NP_001186565NP_001186566NP_001020543NP_031433Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene.

[6][7] PAC1 is a membrane-associated protein and shares significant homology with members of the G-protein coupled class B glucagon/secretin receptor family.

[5] PAC1 is expressed in the adrenal medulla, pancreatic acini, uterus, myenteric plexus and brain.

[9][10][11] It is also expressed in the trigeminal, otic and superior cervical ganglia (prejunctional) and cerebral arteries (postjunctional).

[12] This article incorporates text from the United States National Library of Medicine, which is in the public domain.