The move took the team from south London, where they had been based since their foundation in 1889, to Milton Keynes, a new city in Buckinghamshire, about 56 miles (90 km) to the northwest of the club's traditional home district Wimbledon.

The tie was accompanied by worldwide press attention[12] and was selected for live coverage by television networks around the world as well as being chosen for broadcast by ITV domestically in the UK.

[14] AFC Wimbledon chief executive Erik Samuelson stated that following discussions with the club's owners, board members would not accept hospitality at Stadium MK on the day of the fixture.

On the 59th-minute, AFC Wimbledon equalised through striker Jack Midson's header, and almost took the lead themselves when Steven Gregory's shot produced a save from MK Dons' goalkeeper David Martin.

The match ended in dramatic fashion when on the 93rd-minute, substitute Jon Otsemobor's was struck by the ball on the back of his boot, resulting in a last gasp 2–1 victory for Milton Keynes Dons.

Following a stalemate in the first half, AFC Wimbledon midfielder Jake Reeves struck just after the hour mark before striker Lyle Taylor added a second soon after to seal the victory.

[17] On 30 January 2021 the first fixture between the two clubs at AFC Wimbledon's new Plough Lane stadium took place, albeit without spectators in attendance due to the COVID-19 pandemic.

[19] In the first contest between the two clubs in front of fans at Plough Lane on 2 March 2024, AFC Wimbledon secured a 1–0 victory following a last-gasp goal from Ronan Curtis in the final minute of added time.

[2] Following the fixture, a local newspaper reported that visiting AFC Wimbledon supporters were responsible for damage caused to "seating, toilet and refreshment facilities" within the stadium.

[21] There were security concerns ahead of the first fixture to take place between the two clubs at AFC Wimbledon's (then) home ground of Kingsmeadow on 14 March 2017.

[22] On 20 December 2017, AFC Wimbledon were charged by the EFL with an alleged breach of league regulations following their home encounter with Milton Keynes Dons on 22 September 2017.

The majority of players who have played for both Wimbledon FC and Milton Keynes Dons were members of the team at the time of the relocation.