APINACA (AKB48, N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide) is a drug that acts as a reasonably potent agonist for the cannabinoid receptors.

[5] It had never previously been reported in the scientific or patent literature, and was first identified by laboratories in Japan in March 2012 as an ingredient in synthetic cannabis smoking blends, along with a related compound APICA.

APINACA was made illegal in Japan in 2012,[8] and was banned as a temporary class drug in New Zealand from 13 July 2012.

APINACA is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.

[13] A forensic standard of APINACA is available, and the compound has been posted on the Forendex website of potential drugs of abuse.